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While B12 shots are often associated with clinical settings and doctor's orders, they're not always prescription-only

The compound was also investigated as PL14736 in early-phase IBD clinical work, as described in a 2008 paper by Klicek and colleagues in Journal of Pharmacological Sciences , though that clinical program was never completed or approved

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This timeframe allows assessment of individual response, opportunity to adjust dosing, and generation of meaningful results without committing to an extended protocol